Dr Craig Russell

Lecturer in Pharmaceutics

Third Year Tutor (MPharm)

School of Life & Health Sciences

Aston University
Aston Triangle
Birmingham
B4 7ET
UK

Room: MB 434h 
Tel:
+44 (0) 121 204 3077
Email: c.russell6@aston.ac.uk

Craig Russell
Craig Russell

I have always had a strong interest in science and in particular human biology, health and disease and the associated interventions. My undergraduate degree in Human Biology mapped onto this interest and included molecular and cellular biology, biochemistry and physiology modules among others, which would carry relevance in the physiology and pharmacology setting I progressed into. I further developed my knowledge and bolstered my interest in these fields during my PhD. During this period, formulation of oral liquid antihypertensives formed the initial stages of my project; here an understanding of the chemical and physical properties of drug molecules as well as drug action on a molecular level in a physiological setting was essential. In vitro and In vivo characterisation of developed formulations utilising cell and rodent based models paved the way for subsequent genomic investigations into intestinal transporter expression profiling using microarray technology and bioinformatics. Cell culture played a key role during a spin off project which I have been developing in parallel with the main path of research which has seen the isolation and characterisation of a novel primary cell line aimed at delineation of gustatory sensation.

PH2502 - Pharmaceutical Microbio/Genomics/Genetics/Immunol  (Module Coordinator)

PH2503 - Medicines Optimisation through Formulation

PH3603 - Pharmaceutical Formulation III 

PH3608 - Personal and Professional Development: Project preparation and pre-registration 

PH4701 - Clinical Pharmaceuticals and Drug Delivery 

PHMCT3 - Pharmaceutics in Practice 

PHM014 - Drug Delivery and Targeting 

PhD in Pharmaceutics

 

BSc(Hons) Human Biology

PGCert - Teaching and Learning in HE


August 2016 – Present: Lecturer in Pharmaceutics at Aston University
October 2014 – July 2016: Lecturer in Physiology and Pharmacology at Coventry University College
February 2014 – June 2014: Lecturer in QbD at Aston University
January 2014 – July 2014: Postdoctoral Researcher at Aston University
September 2010 – December 2014: Studied PHD at Aston University
September 2006 – June 2010: Studied BSc (Hons) Human Biology at Uni. Huddersfield

In my role as a lecturer in pharmaceutics I intend to further advance research into in vitro drug absorption modelling. The aim is to benefit the drug development pipeline through an innovative application of novel approaches to permeability assays including genomic and metabolomic approaches not currently exploited. If successful this holds promise to reduce the number of medicinal products which fail at late stage clinical trials thus saving significant time and money. Concurrently, process development seeks to enhance and advance the technologies and methodologies used in existing drug development areas on a day to day basis. With a focus on formulation the techniques and technologies employed in current research are at the cutting edge of formulation development. Solubilisation and stabilisation of insoluble and sensitive drugs for the formulation of oral liquid medications represents one line of research while elsewhere, recent advances in 3D printing technology and intelligent formulation design are currently being exploited to produce novel solid dosage forms targeting a personalised medicine approach to drug development.

Fellow of the Higher Education Academy

Biochemical Society

United Kingdom and Ireland Controlled Release Society (UKICRS)

Associate member of the Physiological Society 

Craig Russell, Sumyra Begum, Yasar Hussain, Majad Hussain, David Huen, Ayesha S Rahman, Yvonne Perrie and Afzal R Mohammed. (2015) Paediatric Drug Development of Ramipril: Reformulation, In Vitro and In Vivo Evaluation. Journal of Drug Targeting

Craig Russell, Ayesha Rahman and Afzal R Mohammed (2013) Application of genomics, proteomics and metabolomics in drug discovery, development and clinic. Therapeutic Delivery. 4 (3) 395 - 413.

Book Chapters

Afzal R Mohammed and Craig A Russell (2012). Drug Development and Delivery. Integrated Foundations of Pharmacy – Pharmaceutics.

Afzal R. Mohammed, Amr M. ElShaer, Rhys J. Jones, Sheraz Khan, Craig A. Russell (2011) Drug Bioavailability and Gene Profiling: Challenges and Opportunities for Pharmaceutics and Personalised Medicine. Handbook of Personalized Medicine: Advances in Nanotechnology, Drug Delivery and Therapy.  

Other Publications
Affiong Iyire, Craig Russell, Clifford Bailey and Afzal R Mohammed (2014) Investigating buccal cell cultures to enhance assessment of transmucosal drug delivery. UKICRS newsletter.

Harriet Hampshire and Craig Russell (2018) Mapping current trends in 3D printing and the impact on the recent landscape of drug development research. British Journal of Pharmacy. - Article Accepted

Affiong Iyire, Craig Russell, Tom Dennison, Rajith Rajoli, Imran Saleem, Ayesha Rahman, Afzal Mohammed (2018) Optimisation, Validation and Inter-Laboratory Verification of a Reversed Phase HPLC Method for Quantification of Human Recombinant Insulin. Journal of Advances in Biotechnology. 7 (1), 984-998

M Andrei, CA Russell (2018) Evaluation of Methotrexate efficiency in comparison to alternative drugs for the treatment of Psoriasis in the UK adult population: A Systematic Review  International Journal of Drug Research and Technology. 8 (2)

Navneet Kaur and Craig A Russell (2017) Systematic review into the role of genomics in profiling overall drug performance and variability. Research and Reviews: Drug Delivery. 1 (1) 41 – 51

Baldeep Singh Chowlia and Craig Allan Russell (2017) A systematic review examining how ‘omics are applied to drug development research. International Journal of Drug Research and Technology. 7 (4) 162 - 179

Craig Russell, Sumyra Begum, Yasar Hussain, Majad Hussain, David Huen, Ayesha S Rahman, Yvonne Perrie and Afzal R Mohammed. (2015) Paediatric Drug Development of Ramipril: Reformulation, In Vitro and In Vivo Evaluation. Journal of Drug Targeting

Craig Russell, Ayesha Rahman and Afzal R Mohammed (2013) Application of genomics, proteomics and metabolomics in drug discovery, development and clinic. Therapeutic Delivery. 4 (3) 395 - 413.


Book Chapters

Afzal R Mohammed and Craig A Russell (2012). Drug Development and Delivery. Integrated Foundations of Pharmacy – Pharmaceutics.

Afzal R. Mohammed, Amr M. ElShaer, Rhys J. Jones, Sheraz Khan, Craig A. Russell (2011) Drug Bioavailability and Gene Profiling: Challenges and Opportunities for Pharmaceutics and Personalised Medicine. Handbook of Personalized Medicine: Advances in Nanotechnology, Drug Delivery and Therapy.  


Other Publications

Craig Russell (2016) We can get by with a little help from our friends [Editorial]. Research and Reviews: Drug Delivery. 1 (1) 3 - 5  

Affiong Iyire, Craig Russell, Clifford Bailey and Afzal R Mohammed (2014) Investigating buccal cell cultures to enhance assessment of transmucosal drug delivery. UKICRS newsletter.


Conference Proceedings and Attendance

UKICRS 2018 – Janki Dahya and Craig Russell (2018) Design, development and evaluation of SLA 3D printed drug transport chambers for in vitro prediction of drug absorption – Poster Presentation 

UKICRS 2018 – Carlo Curti and Craig Russell (2018) Development of a biocompatible SLA printable resin for controlled release 3d printed tablets– Poster Presentation 

UKICRS 2018 – Peter Stone, Craig Russell, Jerome Kroonen, Yvonne Perrie & Alex Rozhin (2018) A comparison between different surfactants for dispersion of carbon nanotubes – Poster Presentation 

RPS Winter Summit 2017 - Jennifer Powley and Craig Russell (2017) Development of an Isosorbide Mononitrate Oral Solution Targeting Optimised Drug Delivery for an Ageing Population. – Poster Presentation 

Biotechnology 2017 Toronto - Craig A. Russell, Madjid Hussain, Qamar Nawaz, Amar Nawaz, Yvonne Perrie and Afzal R. Mohammed (2017) Application of microarrays to develop an in vitro – in vivo correlation screening toolbox – Invited Oral Presentation 

Biotechnology 2017 Toronto – Organising committee member and conference moderator

NDDS 2017 Philadelphia - Craig A. Russell, Madjid Hussain, Qamar Nawaz, Amar Nawaz, Yvonne Perrie and Afzal R. Mohammed (2017) Reformulation of spironolactone to produce an age appropriate oral liquid dosage form targeting the paediatric patient segment – Invited Oral Presentation

APS UK PharmSci 2017 - Peter Stone, Alex Rozhin, Craig Russell, Jerome Kroonen & Yvonne Perrie (2017) A study into how plastic composition affects liposome size reduction efficiency using the bioruptor® plus bath sonicator – Poster Presentation

APS UK PharmSci 2017 - Jennifer Powley and Craig Russell (2017) Development of an isosorbide mononitrate oral solution to achieve optimised drug delivery for an aging population – Poster Presentation 

UKICRS Symposium 2017 - Jennifer Powley and Craig Russell (2017) High throughput HPLC method development and validation for the quantitative evaluation of a recently developed oral isosorbide mononitrate solution – Poster Presentation

UKICRS Symposium 2017 – Mojtaba Nouri and Craig Russell (2017) Development and quantitative evaluation of a recently developed oral chlorothiazide solution – Poster Presentation

UKICRS Symposium 2017 – Omobolanle Bello and Craig Russell (2017) High throughput HPLC method development and validation for the quantitative evaluation of a recently developed oral losartan formulation – Poster Presentation

UKICRS Symposium 2017 - Peter Stone, Alex Rozhin, Craig Russell, Jerome Kroonen & Yvonne Perrie (2017) A study into how plastic composition affects liposome size reduction efficiency using the bioruptor® plus bath sonicator – Poster Presentation

APS UK PharmSci 2012 - Craig A. Russell, Madjid Hussain, Qamar Nawaz, Amar Nawaz, Yvonne Perrie and Afzal R. Mohammed (2012) Development and optimisation of an age appropriate spironolactone formulation – Poster Presentation

UKICRS Symposium 2012 – Craig A. Russell, Madjid Hussain, Qamar Nawaz, Amar Nawaz, Yvonne Perrie and Afzal R. Mohammed (2012) Development and optimisation of an age appropriate spironolactone formulation – Poster Presentation

APS UK PharmSci 2011 - Craig A. Russell, Madjid Hussain, Qamar Nawaz, Amar Nawaz, Yvonne Perrie and Afzal R. Mohammed (2011) Factors to consider during the reformulation of ramipril – Poster Presentation