School of Life & Health Sciences
Aston University Aston Triangle Birmingham B4 7ET
Tel: +44 (0) 121 204 5011 Email: email@example.com Room: MB438C Lab: MB327
I joined Aston University in 2016 as a Lecturer in Microbiology in the School of Life & Health Sciences (LHS). Prior to that, I was a Research Fellow funded by the Tres Cantos Open Lab Foundation (TCOLF), operated by GlaxoSmithKline (GSK), Madrid under their Diseases in the Developing World directive. I was also previously a Research Associate in the Institute of Microbiology and Infection (IMI) at the University of Birmingham immediately after completing my PhD in Molecular Microbiology and Drug Discovery. Before that, I completed an undergraduate degree in Medical Biochemistry at University of Birmingham, where my interest in the biology and biochemistry of microorganisms began.
Abrahams KA*, Cox JAG*, Spivey VL, Loman NJ, Pallen MJ, et al. (2012) Identification of Novel Imidazo[1,2-a]pyridine Inhibitors Targeting M. tuberculosis QcrB. PLoS ONE 7(12): e52951. doi:10.1371/journal.pone.0052951 *These authors contributed equally to this work
Gurcha S, Veeraraghavan U, Cox JAG, Futterer K, Abrahams K, Bhatt A, Alderwick L, Reynolds R, Loman N, Alemparte C, Barros D, Lloyd A, Ballell L and Besra G (2014). Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS. PLoS ONE 9(11): e113568. doi:10.1371/journal.pone.0113568
Mugumbate G, Abrahams KA, Cox JAG, Papadatos G, van Westen G, et al. (2015) Mycobacterial Dihydrofolate Reductase Inhibitors Identified Using Chemogenomic Methods and In Vitro Validation. PLoS ONE 10(3): e0121492. doi:10.1371/journal.pone.0121492
Jankute M, Cox JAG, Harrison J and Besra G (2015). Assembly of the mycobacterial wall. Annual Review of Microbiology 69:405-423
Cox JAG*, Abrahams K*, Alemparte C, Ghidelli-Disse S, Rullas J, Singh A, Gurcha S, Nataraj V, Remuiñan M, Encinas L, Jervis P, Bhatt A, Kruse U, Bantscheff M, Fütterer K, Barros D, Ballell L, Drewes G and Besra G (2016). Target assignment of THPP inhibitors reveals EchA6 as an essential fatty acid shuttle in mycobacteria. Nature Microbiology 1(15006): doi:10.1038/nmicrobiol.2015.6
Abrahams KA, Chung C, Ghidelli-Disse S, Rullas J, Rebollo-Lopez M, Gurcha SS, Cox JAG et al. (2016). A new anti-tubercular scaffold targets KasA with a novel mode of action. Nature Communications 7(12581):doi:10.1038/ncomms12581
Cox JAG, Worthington T (2016). The ‘Antibiotic Apocalypse’ - Scaremongering or Scientific Reporting? Trends in Microbiology http://dx.doi.org/10.1016/j.tim.2016.11.016
Cox JAG, Mugumbate G, Vela-Glez Del Peral L, Jankute M, Abrahams KA et al. (2016). Novel inhibitors of Mycobacterium tuberculosis GuaB2 identified by a target based high-throughput screen. Scientific Reports doi: 10.1038/srep38986 http://www.nature.com/articles/srep38986
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