Dr Gopi Kolluru

Gopi Kolloru

I joined Aston Medical School in July 2015 after spending 5 years as a Postdoctoral Fellow at Department of Pathology/ Center for Cardiovascular Disease and Sciences at the Louisiana State University. I have worked in the fields of Nitric oxide (NO) and Hydrogen sulfide (H2S) signaling, cardiovascular pathophysiology, ischemic revascularization and therapeutics during this time. I have been working in the field of vascular biology starting with my Ph.D at Anna University, where I have studied the Nitric oxide and eNOS signaling mechanisms in relation to shear stress and hypoxia.

Currently I am studying the role of Cystathionine- γ lyase (CSE)/H2S signaling effects during diabetes and pregnancy complications including preeclampsia.

  • Position:  Research Fellow
  • Telephone: 0121 204 4081
  • Email: g.kolluru@aston.ac.uk
  • Room Number: MB319
  • B.Sc with First Class in Biotechnology, Andhra University, Visakhapatnam India, 2000
  • M.Sc with First Class in Microbiology, Andhra University, 2002
  • PhD in Vascular Biology, Anna University, Chennai India, 2011


  • 2015 – Current: Research Fellow, Aston Medical School, Aston University. 
  • 2010 – 2015: Postdoctoral Fellow in Dept. of Pathology/Center for Cardiovascular Diseases, Louisiana State University, Shreveport, USA.
  • 2006 – 2010: Senior Research Fellow, AU-KBC Research Centre, Anna University, India.
  • 2005 – 2006: Junior Research Fellow, AU-KBC Research Centre, Anna University, India
  • 2003 – 2004: Project Assistant, The Centre for Genomic Applications, Delhi University, India
  • 2002 – 2003: QA Executive, The Coca-Cola India


Vascular Pathology, Immunology and inflammation for Allied Health students, LSU Health Shreveport, USA
  • H2S/NO interactions and signaling in vascular biology
  • CSE/H2S role in diabetes and preeclampsia
  • Angiogenesis signaling
  • Molecular therapeutics for diabetes and preeclampsia
  • Ischemic revascularization
  • Protein modifications 


Malcolm Feist Cardiovascular Endowment, LSU, USA
  • American Heart Association (PVD Council)
  • Society for Redox Biology and Medicine (SFRBM) 
  • Nitric Oxide Society


Book Chapters:

Kolluru GK, Yuan S, Kevil CG. H2S regulation of nitric oxide metabolism. Hydrogen Sulfide in Redox Biology Part A & B. Methods in Enzymology 2015;554:271-97.

Shen X, Kolluru GK, Shuai Y, Kevil CG. Measurement of H2S In Vivo and In Vitro by the Monobromobimane Method. Methods in Enzymology 2015;554:31-45.


Peer reviewed publications:

Kolluru GK, Bir SC, Yuan S, Wang R, Kevil CG. Cystathionine γ-lyase regulates arteriogenesis through NO dependent monocyte recruitment. Cardiovasc. Res. 2015.

Bir SC, Pattillo CB, Pardue S, Kolluru GK, Shen X, Giordano T, Kevil CG. Nitrite anion therapy protects against chronic ischemic tissue injury in db/db diabetic mice in a NO/VEGF-dependent manner. Diabetes. 2014 Jan;63(1):270-81. 

Kolluru GK, Shen X, Bir SC, Kevil CG. Hydrogen sulfide chemical biology: pathophysiological roles and detection. Nitric Oxide. 2013 Nov 30;35:5-20. 

Kolluru GK, Shen X, Kevil CG.A tale of two gases: NO and H2S, foes or friends for life? Redox Biol. 2013 May 23;1(1):313-8. 

Kolluru GK, Kevil CG. Beets, bacteria, and blood flow: a lesson of three Bs. Circulation. 2012 Oct 16;126(16):1939-40. 

Kolluru GK, Bir SC, Kevil CG. Endothelial dysfunction and diabetes: effects on angiogenesis, vascular remodeling, and wound healing. Int J Vasc Med. 2012; 2012:918267.

Bir SC, Pattillo CB, Pardue S, Kolluru GK, Docherty J, Goyette D, Dvorsky P, Kevil CG. Nitrite anion stimulates ischemic arteriogenesis involving NO metabolism. Am J Physiol Heart Circ Physiol. 2012 Jul 15;303(2):H178-88.  

Bir SC, Kolluru GK, McCarthy P, Shen X, Pardue S, Pattillo CB, Kevil CG. Hydrogen sulfide stimulates ischemic vascular remodeling through nitric oxide synthase and nitrite reduction activity regulating hypoxia-inducible factor-1α and vascular endothelial growth factor-dependent angiogenesis. J Am Heart Assoc. 2012 Oct;1(5):e004093. 

Bir SC, Pattillo CB, Pardue S, Kolluru GK, Docherty J, Goyette D, Dvorsky P, Kevil CG. Nitrite anion stimulates ischemic arteriogenesis involving NO metabolism. Am J Physiol Heart Circ Physiol. 2012 Jul 15;303(2):H178-88. 

Kolluru GK, Sinha S, Majumder S, Muley A, Siamwala JH, Gupta R, Chatterjee S. Shear stress promotes nitric oxide production in endothelial cells by sub-cellular delocalization of eNOS: A basis for shear stress mediated angiogenesis. Nitric Oxide 2010;22(4):304-15.